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Relating protein crystal structure to ligand-binding thermodynamics

An important interface between biophysical chemistry and biological crystal structures involves whether it is possible to relate experimental calorimetry measurements of protein ligand binding to 3D structures. This has proved to be challenging. The probes of the structure of matter, namely X-rays,...

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Detalles Bibliográficos
Autor principal: Helliwell, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716570/
https://www.ncbi.nlm.nih.gov/pubmed/36458619
http://dx.doi.org/10.1107/S2053230X22011244