Increased copy number of imprinted genes in the chromosomal region 20q11-q13.32 is associated with resistance to antitumor agents in cancer cell lines

BACKGROUND: Parent of origin-specific allelic expression of imprinted genes is epigenetically controlled. In cancer, imprinted genes undergo both genomic and epigenomic alterations, including frequent copy number changes. We investigated whether copy number loss or gain of imprinted genes in cancer...

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Detalles Bibliográficos
Autores principales: Krushkal, Julia, Vural, Suleyman, Jensen, Travis L., Wright, George, Zhao, Yingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716673/
https://www.ncbi.nlm.nih.gov/pubmed/36461044
http://dx.doi.org/10.1186/s13148-022-01368-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716673/
https://www.ncbi.nlm.nih.gov/pubmed/36461044
http://dx.doi.org/10.1186/s13148-022-01368-7

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