Double knockout CRISPR screen for cancer resistance to T cell cytotoxicity

Immunotherapy has transformed cancer treatments; however, a large fraction of patients encounter resistance. Such resistance is mediated by complex factors, often involving interactions between multiple genes. Thus, it is crucially important to identify genetic interactions between genes that are si...

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Detalles Bibliográficos
Autores principales: Park, Jonathan J., Codina, Adan, Ye, Lupeng, Lam, Stanley, Guo, Jianjian, Clark, Paul, Zhou, Xiaoyu, Peng, Lei, Chen, Sidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716677/
https://www.ncbi.nlm.nih.gov/pubmed/36456981
http://dx.doi.org/10.1186/s13045-022-01389-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716677/
https://www.ncbi.nlm.nih.gov/pubmed/36456981
http://dx.doi.org/10.1186/s13045-022-01389-y

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