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SLC22A3 methylation-mediated gene silencing predicts adverse prognosis in acute myeloid leukemia

BACKGROUND: We screened out several hypermethylated solute carrier (SLC) family genes in acute myeloid leukemia by reduced representation bisulfite sequencing. SLC22A3 encodes an organic cation transport protein, which is critical for drug transportation and cellular detoxification. SLC22A3 is signi...

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Detalles Bibliográficos
Autores principales: Gu, Yu, Xu, Zi-jun, Zhou, Jing-dong, Wen, Xiang-mei, Jin, Ye, Yuan, Qian, Xia, Pei-hui, Feng, Yuan, Yang, Lei, Lin, Jiang, Qian, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716704/
https://www.ncbi.nlm.nih.gov/pubmed/36461046
http://dx.doi.org/10.1186/s13148-022-01373-w