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SLC22A3 methylation-mediated gene silencing predicts adverse prognosis in acute myeloid leukemia
BACKGROUND: We screened out several hypermethylated solute carrier (SLC) family genes in acute myeloid leukemia by reduced representation bisulfite sequencing. SLC22A3 encodes an organic cation transport protein, which is critical for drug transportation and cellular detoxification. SLC22A3 is signi...
Autores principales: | Gu, Yu, Xu, Zi-jun, Zhou, Jing-dong, Wen, Xiang-mei, Jin, Ye, Yuan, Qian, Xia, Pei-hui, Feng, Yuan, Yang, Lei, Lin, Jiang, Qian, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716704/ https://www.ncbi.nlm.nih.gov/pubmed/36461046 http://dx.doi.org/10.1186/s13148-022-01373-w |
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