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PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders

BACKGROUND: Neurocognitive disorders and psychosocial difficulties are common in patients with Turner syndrome and multiple neurodegenerative diseases, yet there is no effective cure. Human primordial germ cells (hPGCs) are pluripotent germline stem cells in early embryo, which pass genetic informat...

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Detalles Bibliográficos
Autores principales: Shang, Dantong, Lan, Tian, Wang, Yue, Li, Xuanyu, Liu, Quanyi, Dong, Huimin, Xu, Bo, Cheng, Hanhua, Zhou, Rongjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716775/
https://www.ncbi.nlm.nih.gov/pubmed/36457060
http://dx.doi.org/10.1186/s13578-022-00925-0