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Z-DNA enhances immunotherapy by triggering death of inflammatory cancer-associated fibroblasts

Cancer-associated fibroblasts (CAFs) are a heterogeneous population of cells. At one end of the spectrum are alpha-smooth muscle actin expressing myoCAFs (myofibroblast CAFs) and at the other end are the interferon (IFN) and Janus Kinase/Signal Transducer and Activator of Transcription responsive iC...

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Detalles Bibliográficos
Autores principales: Herbert, Alan, Balachandran, Siddharth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716847/
https://www.ncbi.nlm.nih.gov/pubmed/36450382
http://dx.doi.org/10.1136/jitc-2022-005704