Dasatinib for treatment of CAR T-cell therapy-related complications

Cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) are severe, potentially life-threatening side effects of chimeric antigen receptor T-cell (CAR T) therapy caused by the release of cytokines by proliferating and activated CAR T-cells. Current mainstay...

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Detalles Bibliográficos
Autores principales: Baur, Katharina, Heim, Dominik, Beerlage, Astrid, Poerings, Anna S, Kopp, Bastian, Medinger, Michael, Dirks, Jan C, Passweg, Jakob R, Holbro, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717332/
https://www.ncbi.nlm.nih.gov/pubmed/36455991
http://dx.doi.org/10.1136/jitc-2022-005956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717332/
https://www.ncbi.nlm.nih.gov/pubmed/36455991
http://dx.doi.org/10.1136/jitc-2022-005956

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