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Dysregulated long non-coding RNA in Sjögren’s disease impacts both interferon and adaptive immune responses

OBJECTIVE: Sjögren’s disease (SjD) is an autoimmune disease characterised by inflammatory destruction of exocrine glands. Patients with autoantibodies to Ro/SSA (SjD(Ro+)) exhibit more severe disease. Long non-coding RNAs (lncRNAs) are a functionally diverse class of non-protein-coding RNAs whose ro...

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Detalles Bibliográficos
Autores principales: Joachims, Michelle L, Khatri, Bhuwan, Li, Chuang, Tessneer, Kandice L, Ice, John A, Stolarczyk, Anna M, Means, Nicolas, Grundahl, Kiely M, Glenn, Stuart B, Kelly, Jennifer A, Lewis, David M, Radfar, Lida, Stone, Donald U, Guthridge, Joel M, James, Judith A, Scofield, R Hal, Wiley, Graham B, Wren, Jonathan D, Gaffney, Patrick M, Montgomery, Courtney G, Sivils, Kathy L, Rasmussen, Astrid, Farris, A Darise, Adrianto, Indra, Lessard, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717416/
https://www.ncbi.nlm.nih.gov/pubmed/36456101
http://dx.doi.org/10.1136/rmdopen-2022-002672