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In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-κB modulator in lung cancer

Systemic identification of tumor suppressor genes (TSGs) and elucidation of their signaling provide a new angle for understanding of tumorigenesis, which is important for developing successful treatment for lung cancer patients. In our current work, we conducted an in vivo screen for lung cancer TSG...

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Detalles Bibliográficos
Autores principales: Liu, Lu, Lei, Yuxi, Chen, Wensheng, Zhou, Qian, Zheng, Zongyao, Zeng, Guandi, Liu, Wanting, Feng, Pengju, Zhang, Zhiyi, Yu, Lei, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717477/
https://www.ncbi.nlm.nih.gov/pubmed/36457047
http://dx.doi.org/10.1186/s13578-022-00933-0