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Generalized nuclear localization of retroelement transcripts

BACKGROUND: LINE-1s, Alus and SVAs are the only retrotransposition competent elements in humans. Their mobilization followed by insertional mutagenesis is often linked to disease. Apart from these rare integration events, accumulation of retrotransposition intermediates in the cytoplasm is potential...

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Detalles Bibliográficos
Autores principales: Das, Simanti, Jones, Amanda E., Abrams, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717504/
https://www.ncbi.nlm.nih.gov/pubmed/36461093
http://dx.doi.org/10.1186/s13100-022-00287-x