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Expression of Synj2bp in mouse liver regulates the extent of wrappER-mitochondria contact to maintain hepatic lipid homeostasis

BACKGROUND: In mouse liver hepatocytes, nearly half of the surface area of every mitochondrion is covered by wrappER, a wrapping-type of ER that is rich in fatty acids and synthesizes lipoproteins (VLDL) (Anastasia et al. in Cell Rep 34:108873, 2021; Hurtley in Science (80- ) 372:142–143, 2021; Ilac...

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Detalles Bibliográficos
Autores principales: Ilacqua, Nicolò, Anastasia, Irene, Aloshyn, Danylo, Ghandehari-Alavijeh, Rana, Peluso, Emily Ann, Brearley-Sholto, Madelaine C., Pellegrini, Leonardo V., Raimondi, Andrea, de Aguiar Vallim, Thomas Q., Pellegrini, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717519/
https://www.ncbi.nlm.nih.gov/pubmed/36457006
http://dx.doi.org/10.1186/s13062-022-00344-8