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MicroRNA-378a-3p prevents initiation and growth of colorectal cancer by fine tuning polyamine synthesis
BACKGROUND: Inhibitors of ornithine decarboxylase (ODC) are effective at preventing colorectal cancer (CRC). However, their high toxicity limits their clinical application. This study was aimed to explore the potential of microRNAs (miRNAs) as an inhibitor of ODC. METHODS: miRNA array was used to id...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717536/ https://www.ncbi.nlm.nih.gov/pubmed/36457036 http://dx.doi.org/10.1186/s13578-022-00930-3 |