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A synthetic pregnenolone analog promotes microtubule dynamics and neural development

BACKGROUND: Pregnenolone (P5) is a neurosteroid that promotes microtubule polymerization. It also reduces stress and negative symptoms of schizophrenia, promotes memory, as well as recovery from spinal cord injury. P5 is the first substance in the steroid-synthetic pathway; it can be further metabol...

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Detalles Bibliográficos
Autores principales: Kolas, Viktoryia, Bandonil, Jose Sandino A., Wali, Niaz, Hsia, Kuo-Chiang, Shie, Jiun-Jie, Chung, Bon-chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717551/
https://www.ncbi.nlm.nih.gov/pubmed/36456994
http://dx.doi.org/10.1186/s13578-022-00923-2