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A synthetic pregnenolone analog promotes microtubule dynamics and neural development
BACKGROUND: Pregnenolone (P5) is a neurosteroid that promotes microtubule polymerization. It also reduces stress and negative symptoms of schizophrenia, promotes memory, as well as recovery from spinal cord injury. P5 is the first substance in the steroid-synthetic pathway; it can be further metabol...
Autores principales: | Kolas, Viktoryia, Bandonil, Jose Sandino A., Wali, Niaz, Hsia, Kuo-Chiang, Shie, Jiun-Jie, Chung, Bon-chu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717551/ https://www.ncbi.nlm.nih.gov/pubmed/36456994 http://dx.doi.org/10.1186/s13578-022-00923-2 |
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