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rpoB Mutations are Associated with Variable Levels of Rifampin and Rifabutin Resistance in Mycobacterium tuberculosis

OBJECTIVE: To assess the relationship between the variant rpoB mutations and the degree of rifampin (RIF)/rifabutin (RFB) resistance in Mycobacterium tuberculosis (M. tuberculosis). METHODS: We analyzed the whole rpoB gene in 177 M. tuberculosis clinical isolates and quantified their minimum inhibit...

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Detalles Bibliográficos
Autores principales: Li, Ma-Chao, Wang, Xiao-Yue, Xiao, Tong-Yang, Lin, Shi-Qiang, Liu, Hai-Can, Qian, Cheng, Xu, Da, Li, Gui-Lian, Zhao, Xiu-Qin, Liu, Zhi-Guang, Zhao, Li-Li, Wan, Kang-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717584/
https://www.ncbi.nlm.nih.gov/pubmed/36465812
http://dx.doi.org/10.2147/IDR.S386863