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Population Pharmacokinetics of Levofloxacin and Moxifloxacin, and the Probability of Target Attainment in Ethiopian Patients with Multidrug-Resistant Tuberculosis

OBJECTIVE: This study aimed to explore the population pharmacokinetic modeling (PopPK) of levofloxacin (LFX) and moxifloxacin (MXF), as well as the percent probability of target attainment (PTA) as defined by the ratio of the area under the plasma concentration-time curve over 24 h and the in vitro...

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Detalles Bibliográficos
Autores principales: Sidamo, Temesgen, Rao, Prakruti S, Aklillu, Eleni, Shibeshi, Workineh, Park, Yumi, Cho, Yong-soon, Shin, Jae-Gook, Heysell, Scott K, Mpagama, Stellah G, Engidawork, Ephrem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717595/
https://www.ncbi.nlm.nih.gov/pubmed/36465811
http://dx.doi.org/10.2147/IDR.S389442