The Role of NF-κB and Bax/Bcl-2/Caspase-3 Signaling Pathways in the Protective Effects of Sacubitril/Valsartan (Entresto) against HFD/STZ-Induced Diabetic Kidney Disease

LCZ696 (valsartan/sacubitril) has the potential to slow the progression of diabetic kidney disease (DKD) according to previous reports. However, the renoprotective mechanism underlying LCZ696 remains unknown. This study aimed to investigate the therapeutic potential and underlying mechanism of LCZ69...

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Detalles Bibliográficos
Autores principales: Mohany, Mohamed, Ahmed, Mohammed M., Al-Rejaie, Salim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717728/
https://www.ncbi.nlm.nih.gov/pubmed/36359384
http://dx.doi.org/10.3390/biomedicines10112863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717728/
https://www.ncbi.nlm.nih.gov/pubmed/36359384
http://dx.doi.org/10.3390/biomedicines10112863

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