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Evaluation of two new highly multiplexed PCR assays as an alternative to next‐generation sequencing for IDH1/2 mutation detection

IDH1 and IDH2 somatic mutations have been identified in solid tumors and blood malignancies. The development of inhibitors of mutant IDH1 and IDH2 in the past few years has prompted the development of a fast and sensitive assay to detect IDH1 ( R132 ), IDH2 ( R140 ) and IDH2 ( R172 ) mutations to id...

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Detalles Bibliográficos
Autores principales: Favre, Loetitia, Sako, Nouhoum, Tarfi, Sihem, Quang, Violaine Tran, Joy, Corine, Dupuy, Aurélie, Guillerm, Erell, Gaulard, Philippe, Wagner‐Ballon, Orianne, Pujals, Anaïs, Sloma, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718115/
https://www.ncbi.nlm.nih.gov/pubmed/36062346
http://dx.doi.org/10.1002/1878-0261.13311