Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRα1, in intestinal lesions

The THRA gene, encoding the thyroid hormone nuclear receptor TRα1, is expressed in an increasing gradient at the bottom of intestinal crypts, overlapping with high Wnt and Notch activities. Importantly, THRA is upregulated in colorectal cancers, particularly in the high‐Wnt molecular subtype. The ba...

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Detalles Bibliográficos
Autores principales: Giolito, Maria Virginia, La Rosa, Théo, Farhat, Diana, Bodoirat, Serguei, Guardia, Gabriela D. A., Domon‐Dell, Claire, Galante, Pedro A. F., Freund, Jean‐Noel, Plateroti, Michelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718118/
https://www.ncbi.nlm.nih.gov/pubmed/36217307
http://dx.doi.org/10.1002/1878-0261.13298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718118/
https://www.ncbi.nlm.nih.gov/pubmed/36217307
http://dx.doi.org/10.1002/1878-0261.13298

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