Effect of autotaxin inhibition in a surgically-induced mouse model of osteoarthritis

OBJECTIVE: Osteoarthritis (OA) is a degenerative joint disease with no approved disease modifying therapy. The enzyme autotaxin (ATX) converts lysophoshatidylcholine analogues to lysophosphatidic acid. Systemic inhibition of ATX reduces pain in animal models of OA; however, OA disease-modifying effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Datta, Poulami, Gandhi, Rajiv, Nakamura, Sayaka, Lively, Starlee, Rossomacha, Evgeny, Potla, Pratibha, Shestopaloff, Konstantin, Endisha, Helal, Pastrello, Chiara, Jurisica, Igor, Rockel, Jason S., Kapoor, Mohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
BRIEF REPORT
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718142/
https://www.ncbi.nlm.nih.gov/pubmed/36474685
http://dx.doi.org/10.1016/j.ocarto.2020.100080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718142/
https://www.ncbi.nlm.nih.gov/pubmed/36474685
http://dx.doi.org/10.1016/j.ocarto.2020.100080

Ejemplares similares