CCL2 induces articular chondrocyte MMP expression through ERK and p38 signaling pathways

OBJECTIVE: In previous studies, we determined an association between increased serum and articular cartilage levels of CCL2 with osteoarthritis (OA) progression, cartilage damage and increased MMP13 in cartilage. Here we analyzed CCL2 downstream signaling mediators that lead to gene expression of ca...

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Detalles Bibliográficos
Autores principales: Willcockson, Helen, Ozkan, Huseyin, Chubinskaya, Susan, Loeser, Richard F., Longobardi, Lara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
ORIGINAL PAPER
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718225/
https://www.ncbi.nlm.nih.gov/pubmed/36475068
http://dx.doi.org/10.1016/j.ocarto.2020.100136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718225/
https://www.ncbi.nlm.nih.gov/pubmed/36475068
http://dx.doi.org/10.1016/j.ocarto.2020.100136

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