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Human amniotic membrane modulates Wnt/β-catenin and NF-κβ signaling pathways in articular chondrocytes in vitro

OBJECTIVE: Inflammation, catabolism, and hypertrophy in chondrocytes play a central role in osteoarthritis (OA). The Wnt/β-catenin and NF-κβ pathways contribute to these degradative processes. This in vitro study evaluates the inhibitory effect of a novel therapeutic, micronized dehydrated human amn...

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Detalles Bibliográficos
Autores principales: Chung, Connie, Massee, Michelle, Koob, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718226/
https://www.ncbi.nlm.nih.gov/pubmed/36474757
http://dx.doi.org/10.1016/j.ocarto.2021.100211