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Liver X Receptor activation regulates genes involved in lipid homeostasis in developing chondrocytes

OBJECTIVE: Osteoarthritis (OA) is the most common type of arthritis and causes debilitating symptoms and decreased quality of life. A better understanding of the molecular mechanisms maintaining cartilage health is needed for developing novel therapeutic strategies. Liver X Receptors (LXRs) are nucl...

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Detalles Bibliográficos
Autores principales: Sun, Margaret Man-Ger, Beier, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718240/
https://www.ncbi.nlm.nih.gov/pubmed/36474558
http://dx.doi.org/10.1016/j.ocarto.2020.100030