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Ex vivo osteochondral test system with control over cartilage defect depth – A pilot study to investigate the effect of oxygen tension and chondrocyte based treatments in chondral and full thickness defects in an organ model

OBJECTIVE: Cartilage defect treatment strategies are dependent on the lesion size and severity. Osteochondral explant models are a platform to test cartilage repair strategies ex vivo. Current models lack in mimicking the variety of clinically relevant defect scenarios. In this controlled laboratory...

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Detalles Bibliográficos
Autores principales: Schwab, Andrea, Buss, Alexa, Pullig, Oliver, Ehlicke, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718282/
https://www.ncbi.nlm.nih.gov/pubmed/36474989
http://dx.doi.org/10.1016/j.ocarto.2021.100173