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Systematic proximal mapping of the classical RAD51 paralogs unravel functionally and clinically relevant interactors for genome stability

Homologous recombination (HR) plays an essential role in the maintenance of genome stability by promoting the repair of cytotoxic DNA double strand breaks (DSBs). More recently, the HR pathway has emerged as a core component of the response to replication stress, in part by protecting stalled replic...

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Detalles Bibliográficos
Autores principales: Simo Cheyou, Estelle, Boni, Jacopo, Boulais, Jonathan, Pinedo-Carpio, Edgar, Malina, Abba, Sherill-Rofe, Dana, Luo, Vincent M., Goncalves, Christophe, Bagci, Halil, Maters, Alexandra, Cuella-Martin, Raquel, Tabach, Yuval, del Rincon, Sonia, Côté, Jean-Francois, Rivera, Barbara, Orthwein, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718398/
https://www.ncbi.nlm.nih.gov/pubmed/36374936
http://dx.doi.org/10.1371/journal.pgen.1010495