Yeast-based evolutionary modeling of androgen receptor mutations and natural selection

Cancer progression is associated with the evolutionary accumulation of genetic mutations that are biologically significant. Mutations of the androgen receptor (AR) are associated with the development of prostate cancer (PCa) by responding to non-androgenic hormones, and the lack of annotations in th...

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Detalles Bibliográficos
Autores principales: Zhang, Haoran, Zhang, Lu, Chen, Shaoyong, Yao, Mingdong, Ma, Zhenyi, Yuan, Yingjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718406/
https://www.ncbi.nlm.nih.gov/pubmed/36459502
http://dx.doi.org/10.1371/journal.pgen.1010518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718406/
https://www.ncbi.nlm.nih.gov/pubmed/36459502
http://dx.doi.org/10.1371/journal.pgen.1010518

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