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Response to Hypoxia and the Ensuing Dysregulation of Inflammation Impacts Mycobacterium tuberculosis Pathogenicity

RATIONALE: Different Mycobacterium tuberculosis (Mtb) strains exhibit variable degrees of virulence in humans and animal models. Differing stress response strategies used by different strains of Mtb could influence virulence. OBJECTIVES: We compared the virulence of two strains of Mtb with use in an...

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Detalles Bibliográficos
Autores principales: Bucşan, Allison N., Veatch, Ashley, Singh, Dhiraj K., Akter, Sadia, Golden, Nadia A., Kirkpatrick, Melanie, Threeton, Breanna, Moodley, Chivonne, Ahmed, Mushtaq, Doyle, Lara A., Russell-Lodrigue, Kasi, Norton, Elizabeth B., Didier, Peter J., Roy, Chad J., Abramovitch, Robert B., Mehra, Smriti, Khader, Shabaana A., Kaushal, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718519/
https://www.ncbi.nlm.nih.gov/pubmed/35412961
http://dx.doi.org/10.1164/rccm.202112-2747OC