SRSF6 balances mitochondrial-driven innate immune outcomes through alternative splicing of BAX

To mount a protective response to infection while preventing hyperinflammation, gene expression in innate immune cells must be tightly regulated. Despite the importance of pre-mRNA splicing in shaping the proteome, its role in balancing immune outcomes remains understudied. Transcriptomic analysis o...

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Detalles Bibliográficos
Autores principales: Wagner, Allison R, Weindel, Chi G, West, Kelsi O, Scott, Haley M, Watson, Robert O, Patrick, Kristin L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718523/
https://www.ncbi.nlm.nih.gov/pubmed/36409059
http://dx.doi.org/10.7554/eLife.82244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718523/
https://www.ncbi.nlm.nih.gov/pubmed/36409059
http://dx.doi.org/10.7554/eLife.82244

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