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Ketone body augmentation decreases methacholine hyperresponsiveness in mouse models of allergic asthma

BACKGROUND: Individuals with allergic asthma exhibit lung inflammation and remodeling accompanied by methacholine hyperresponsiveness manifesting in proximal airway narrowing and distal lung tissue collapsibility, and they can present with a range of mild-to-severe disease amenable or resistant to t...

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Detalles Bibliográficos
Autores principales: Mank, Madeleine M., Reed, Leah F., Fastiggi, V. Amanda, Peña-García, Paola E., Hoyt, Laura R., Van Der Vliet, Katherine E., Ather, Jennifer L., Poynter, Matthew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718535/
https://www.ncbi.nlm.nih.gov/pubmed/36466740
http://dx.doi.org/10.1016/j.jacig.2022.08.001