Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci

Despite the large toll of opioid use disorder (OUD), genome-wide association studies (GWAS) of OUD to date have yielded few susceptibility loci. We performed a large-scale GWAS of OUD in individuals of European (EUR) and African (AFR) ancestry, optimizing genetic informativeness by performing MTAG (...

Descripción completa

Detalles Bibliográficos
Autores principales: Deak, Joseph D., Zhou, Hang, Galimberti, Marco, Levey, Daniel F., Wendt, Frank R., Sanchez-Roige, Sandra, Hatoum, Alexander S., Johnson, Emma C., Nunez, Yaira Z., Demontis, Ditte, Børglum, Anders D., Rajagopal, Veera M., Jennings, Mariela V., Kember, Rachel L., Justice, Amy C., Edenberg, Howard J., Agrawal, Arpana, Polimanti, Renato, Kranzler, Henry R., Gelernter, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Immediate Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718667/
https://www.ncbi.nlm.nih.gov/pubmed/35879402
http://dx.doi.org/10.1038/s41380-022-01709-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718667/
https://www.ncbi.nlm.nih.gov/pubmed/35879402
http://dx.doi.org/10.1038/s41380-022-01709-1

Ejemplares similares