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Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci
Despite the large toll of opioid use disorder (OUD), genome-wide association studies (GWAS) of OUD to date have yielded few susceptibility loci. We performed a large-scale GWAS of OUD in individuals of European (EUR) and African (AFR) ancestry, optimizing genetic informativeness by performing MTAG (...
Autores principales: | Deak, Joseph D., Zhou, Hang, Galimberti, Marco, Levey, Daniel F., Wendt, Frank R., Sanchez-Roige, Sandra, Hatoum, Alexander S., Johnson, Emma C., Nunez, Yaira Z., Demontis, Ditte, Børglum, Anders D., Rajagopal, Veera M., Jennings, Mariela V., Kember, Rachel L., Justice, Amy C., Edenberg, Howard J., Agrawal, Arpana, Polimanti, Renato, Kranzler, Henry R., Gelernter, Joel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718667/ https://www.ncbi.nlm.nih.gov/pubmed/35879402 http://dx.doi.org/10.1038/s41380-022-01709-1 |
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