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Medial prefrontal cortex Notch1 signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABA(B1) receptor expression

Methamphetamine (METH), a widely abused stimulant drug, induces psychosis in approximately half of abusers; this effect is becoming a major concern for society. Although the Notch1 signalling pathway has been shown to play a part in the pathogenesis of some psychiatric disorders, its role in METH-in...

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Detalles Bibliográficos
Autores principales: Ni, Tong, Zhu, Li, Wang, Shuai, Zhu, Weili, Xue, Yanxue, Zhu, Yingjie, Ma, Dongliang, Wang, Hongyan, Guan, Fanglin, Chen, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718672/
https://www.ncbi.nlm.nih.gov/pubmed/35732696
http://dx.doi.org/10.1038/s41380-022-01662-z