Detection of m6A from direct RNA sequencing using a multiple instance learning framework

RNA modifications such as m6A methylation form an additional layer of complexity in the transcriptome. Nanopore direct RNA sequencing can capture this information in the raw current signal for each RNA molecule, enabling the detection of RNA modifications using supervised machine learning. However,...

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Detalles Bibliográficos
Autores principales: Hendra, Christopher, Pratanwanich, Ploy N., Wan, Yuk Kei, Goh, W. S. Sho, Thiery, Alexandre, Göke, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718678/
https://www.ncbi.nlm.nih.gov/pubmed/36357692
http://dx.doi.org/10.1038/s41592-022-01666-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718678/
https://www.ncbi.nlm.nih.gov/pubmed/36357692
http://dx.doi.org/10.1038/s41592-022-01666-1

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