Glucocorticoid-glucocorticoid receptor-HCN1 channels reduce neuronal excitability in dorsal hippocampal CA1 neurons

While chronic stress increases hyperpolarization-activated current (I(h)) in dorsal hippocampal CA1 neurons, the underlying molecular mechanisms are entirely unknown. Following chronic social defeat stress (CSDS), susceptible mice displayed social avoidance and impaired spatial working memory, which...

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Detalles Bibliográficos
Autores principales: Kim, Jiwon, Lei, Yun, Lu, Xin-Yun, Kim, Chung Sub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718682/
https://www.ncbi.nlm.nih.gov/pubmed/35840797
http://dx.doi.org/10.1038/s41380-022-01682-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718682/
https://www.ncbi.nlm.nih.gov/pubmed/35840797
http://dx.doi.org/10.1038/s41380-022-01682-9

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