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Glucocorticoid-glucocorticoid receptor-HCN1 channels reduce neuronal excitability in dorsal hippocampal CA1 neurons
While chronic stress increases hyperpolarization-activated current (I(h)) in dorsal hippocampal CA1 neurons, the underlying molecular mechanisms are entirely unknown. Following chronic social defeat stress (CSDS), susceptible mice displayed social avoidance and impaired spatial working memory, which...
Autores principales: | Kim, Jiwon, Lei, Yun, Lu, Xin-Yun, Kim, Chung Sub |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718682/ https://www.ncbi.nlm.nih.gov/pubmed/35840797 http://dx.doi.org/10.1038/s41380-022-01682-9 |
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