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Rho Kinase Inhibitor Y27632 Improves Recovery After Spinal Cord Injury by Shifting Astrocyte Phenotype and Morphology via the ROCK/NF-κB/C3 Pathway

Spinal cord injury (SCI) usually results in loss or reduction in motor and sensory functions. Despite extensive research, no available therapy can restore the lost functions after SCI. Reactive astrocytes play a pivotal role in SCI. Rho kinase inhibitors have also been shown to promote functional re...

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Detalles Bibliográficos
Autores principales: Zhang, Yongyuan, Wang, Xiaohui, Jiang, Chao, Chen, Zhe, Ni, Shuangyang, Fan, Hong, Wang, Zhiyuan, Tian, Fang, An, Jing, Yang, Hao, Hao, Dingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718714/
https://www.ncbi.nlm.nih.gov/pubmed/36103106
http://dx.doi.org/10.1007/s11064-022-03756-0