Cargando…

Low-rank tensor methods for Markov chains with applications to tumor progression models

Cancer progression can be described by continuous-time Markov chains whose state space grows exponentially in the number of somatic mutations. The age of a tumor at diagnosis is typically unknown. Therefore, the quantity of interest is the time-marginal distribution over all possible genotypes of tu...

Descripción completa

Detalles Bibliográficos
Autores principales: Georg, Peter, Grasedyck, Lars, Klever, Maren, Schill, Rudolf, Spang, Rainer, Wettig, Tilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718722/
https://www.ncbi.nlm.nih.gov/pubmed/36460900
http://dx.doi.org/10.1007/s00285-022-01846-9