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Low-rank tensor methods for Markov chains with applications to tumor progression models
Cancer progression can be described by continuous-time Markov chains whose state space grows exponentially in the number of somatic mutations. The age of a tumor at diagnosis is typically unknown. Therefore, the quantity of interest is the time-marginal distribution over all possible genotypes of tu...
Autores principales: | Georg, Peter, Grasedyck, Lars, Klever, Maren, Schill, Rudolf, Spang, Rainer, Wettig, Tilo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718722/ https://www.ncbi.nlm.nih.gov/pubmed/36460900 http://dx.doi.org/10.1007/s00285-022-01846-9 |
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