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Chemoenzymatic synthesis of sulfur-linked sugar polymers as heparanase inhibitors
Complex carbohydrates (glycans) are major players in all organisms due to their structural, energy, and communication roles. This last essential role involves interacting and/or signaling through a plethora of glycan-binding proteins. The design and synthesis of glycans as potential drug candidates...
Autores principales: | He, Peng, Zhang, Xing, Xia, Ke, Green, Dixy E., Baytas, Sultan, Xu, Yongmei, Pham, Truong, Liu, Jian, Zhang, Fuming, Almond, Andrew, Linhardt, Robert J., DeAngelis, Paul L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718760/ https://www.ncbi.nlm.nih.gov/pubmed/36460670 http://dx.doi.org/10.1038/s41467-022-34788-3 |
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