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A growth selection system for the directed evolution of amine-forming or converting enzymes
Fast screening of enzyme variants is crucial for tailoring biocatalysts for the asymmetric synthesis of non-natural chiral chemicals, such as amines. However, most existing screening methods either are limited by the throughput or require specialized equipment. Herein, we report a simple, high-throu...
Autores principales: | Wu, Shuke, Xiang, Chao, Zhou, Yi, Khan, Mohammad Saiful Hasan, Liu, Weidong, Feiler, Christian G., Wei, Ren, Weber, Gert, Höhne, Matthias, Bornscheuer, Uwe T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718777/ https://www.ncbi.nlm.nih.gov/pubmed/36460668 http://dx.doi.org/10.1038/s41467-022-35228-y |
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