Nascent peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes

Robust translation elongation of any given amino acid sequence is required to shape proteomes. Nevertheless, nascent peptides occasionally destabilize ribosomes, since consecutive negatively charged residues in bacterial nascent chains can stochastically induce discontinuation of translation, in a p...

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Detalles Bibliográficos
Autores principales: Ito, Yosuke, Chadani, Yuhei, Niwa, Tatsuya, Yamakawa, Ayako, Machida, Kodai, Imataka, Hiroaki, Taguchi, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718836/
https://www.ncbi.nlm.nih.gov/pubmed/36460666
http://dx.doi.org/10.1038/s41467-022-35156-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718836/
https://www.ncbi.nlm.nih.gov/pubmed/36460666
http://dx.doi.org/10.1038/s41467-022-35156-x

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