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Nascent peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes
Robust translation elongation of any given amino acid sequence is required to shape proteomes. Nevertheless, nascent peptides occasionally destabilize ribosomes, since consecutive negatively charged residues in bacterial nascent chains can stochastically induce discontinuation of translation, in a p...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718836/ https://www.ncbi.nlm.nih.gov/pubmed/36460666 http://dx.doi.org/10.1038/s41467-022-35156-x |