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NRG1 knockdown rescues PV interneuron GABAergic maturation deficits and schizophrenia behaviors in fetal growth restriction mice

Schizophrenia is a highly debilitating mental disorder, those who experienced fetal growth restriction (FGR) in the early stage of life have a greater probability of schizophrenia. In this study, FGR mice showed hyperactivity in locomotor activity test, sociability dysfunction in three chamber test...

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Detalles Bibliográficos
Autores principales: Dong, Jianfeng, Chen, Wen, Liu, Nana, Chang, Shujuan, Zhu, Wei, Kang, Jiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718849/
https://www.ncbi.nlm.nih.gov/pubmed/36460658
http://dx.doi.org/10.1038/s41420-022-01271-3