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Reduced excitatory neuron activity and interneuron-type-specific deficits in a mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is characterized by progressive memory loss and cognitive decline. These impairments correlate with early alterations in neuronal network activity in AD patients. Disruptions in the activity of individual neurons have been reported in mouse models of amyloidosis. However, th...

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Detalles Bibliográficos
Autores principales: Algamal, Moustafa, Russ, Alyssa N., Miller, Morgan R., Hou, Steven S., Maci, Megi, Munting, Leon P., Zhao, Qiuchen, Gerashchenko, Dmitry, Bacskai, Brian J., Kastanenka, Ksenia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718858/
https://www.ncbi.nlm.nih.gov/pubmed/36460716
http://dx.doi.org/10.1038/s42003-022-04268-x