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Metabolism-dependent ferroptosis promotes mitochondrial dysfunction and inflammation in CD4(+) T lymphocytes in HIV-infected immune non-responders
BACKGROUND: HIV immune non-responders (INRs) are described as a failure to reestablish a pool of CD4(+) T lymphocytes (CD4 cells) after antiretroviral therapy (ART), which is related to poor clinical results. Ferroptosis is a newly discovered form of cell death characterised by iron-dependent lipid...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718960/ https://www.ncbi.nlm.nih.gov/pubmed/36462403 http://dx.doi.org/10.1016/j.ebiom.2022.104382 |