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Metabolism-dependent ferroptosis promotes mitochondrial dysfunction and inflammation in CD4(+) T lymphocytes in HIV-infected immune non-responders

BACKGROUND: HIV immune non-responders (INRs) are described as a failure to reestablish a pool of CD4(+) T lymphocytes (CD4 cells) after antiretroviral therapy (ART), which is related to poor clinical results. Ferroptosis is a newly discovered form of cell death characterised by iron-dependent lipid...

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Detalles Bibliográficos
Autores principales:	Xiao, Qing, Yan, Liting, Han, Junyan, Yang, Siyuan, Tang, Yunxia, Li, Qun, Lao, Xiaojie, Chen, Zhen, Xiao, Jiang, Zhao, Hongxin, Yu, Fengting, Zhang, Fujie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718960/ https://www.ncbi.nlm.nih.gov/pubmed/36462403 http://dx.doi.org/10.1016/j.ebiom.2022.104382

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