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GTKO rabbit: A novel animal model for preclinical assessment of decellularized xenogeneic grafts via in situ implantation

Wild type (WT) animals cannot be used to objectively assess the immunogenicity of animal tissue-derived biomaterials when used as recipients due to difference with human in α-Gal expression. The purpose of this study is to compare the differences of immunological responses between the GGTA1 gene-kno...

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Detalles Bibliográficos
Autores principales: Mu, Yufeng, Zhang, Yu, Wei, Lina, Chen, Liang, Hao, Feng, Shao, Anliang, Qu, Shuxin, Xu, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719100/
https://www.ncbi.nlm.nih.gov/pubmed/36471894
http://dx.doi.org/10.1016/j.mtbio.2022.100505