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Longitudinal monitoring of cell-free DNA methylation in ALK-positive non-small cell lung cancer patients

BACKGROUND: DNA methylation (5-mC) signals in cell-free DNA (cfDNA) of cancer patients represent promising biomarkers for minimally invasive tumor detection. The high abundance of cancer-associated 5-mC alterations permits parallel and highly sensitive assessment of multiple 5-mC biomarkers. Here, w...

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Detalles Bibliográficos
Autores principales: Janke, Florian, Angeles, Arlou Kristina, Riediger, Anja Lisa, Bauer, Simone, Reck, Martin, Stenzinger, Albrecht, Schneider, Marc A., Muley, Thomas, Thomas, Michael, Christopoulos, Petros, Sültmann, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719130/
https://www.ncbi.nlm.nih.gov/pubmed/36461127
http://dx.doi.org/10.1186/s13148-022-01387-4