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Shaking up the silence: consequences of HMGN1 antagonizing PRC2 in the Down syndrome brain

Intellectual disability is a well-known hallmark of Down Syndrome (DS) that results from the triplication of the critical region of human chromosome 21 (HSA21). Major studies were conducted in recent years to gain an understanding about the contribution of individual triplicated genes to DS-related...

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Detalles Bibliográficos
Autores principales: Farley, Sean J., Grishok, Alla, Zeldich, Ella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719135/
https://www.ncbi.nlm.nih.gov/pubmed/36463299
http://dx.doi.org/10.1186/s13072-022-00471-6